Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922456 | 1.00 | GRM5 (1.00) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3929004 | 0.86 | GRM5 (0.76) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL5217879 | 0.86 | GRM5 (0.76) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL5216403 | 0.85 | GRM5 (0.74) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3931395 | 0.84 | GRM5 (0.72) | GRM5IRAK4 | |
| SCHEMBL5667534 | 0.84 | GRM5 (0.71) | GRM5 | |
| SCHEMBL19902102 | 0.82 | GRM5 (0.70) | GRM5IRAK4 | |
| SCHEMBL3934307 | 0.82 | GRM5 (0.70) | GRM5IRAK4 | |
| SCHEMBL5667022 | 0.81 | GRM5 (0.68) | GRM5 | |
| SCHEMBL5220524 | 0.81 | GRM5 (0.68) | GRM5KDM4EALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |