Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928288 | 0.83 | GRM5 (0.50) | GRM5NOTUMGABRA1GABRG2GABRB3 | |
| SCHEMBL5216403 | 0.83 | GRM5 (0.74) | GRM5NOTUMAXLCHRNB2CHRNA5 | |
| SCHEMBL3922456 | 0.82 | GRM5 (1.00) | GRM5IRAK4 | |
| SCHEMBL30795243 | 0.82 | GRM5 (1.00) | GRM5IRAK4 | |
| SCHEMBL3921645 | 0.79 | GRM5 (0.58) | GRM5NOTUMIRAK4DRD2DRD3 | |
| SCHEMBL515503 | 0.79 | GAA (0.59) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3929004 | 0.79 | GRM5 (0.76) | GRM5NOTUMAXLCHRNB2CHRNA5 | |
| SCHEMBL5220524 | 0.79 | GRM5 (0.68) | GRM5NOTUMAXL | |
| SCHEMBL5216877 | 0.78 | GRM5 (0.67) | GRM5NOTUMIRAK4AXL | |
| SCHEMBL5215750 | 0.78 | GRM5 (0.63) | GRM5NOTUMAXLCHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9905785-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |