Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929713 | 1.00 | GRM5 (0.57) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL3931406 | 0.90 | GRM5 (0.51) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL30795646 | 0.87 | GRM5 (0.71) | GRM5KDM4EHTTALDH1A1CRHR1 | |
| SCHEMBL3920978 | 0.87 | GRM5 (0.71) | GRM5KDM4EHTTALDH1A1CRHR1 | |
| SCHEMBL30795324 | 0.82 | GRM5 (0.64) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL3923785 | 0.82 | GRM5 (0.64) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL3929805 | 0.81 | GRM5 (0.57) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL5219536 | 0.81 | GRM5 (0.57) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL5215879 | 0.79 | GRM5 (0.54) | GRM5KDM4ELMNACCR1CCR5 | |
| SCHEMBL3926081 | 0.78 | GRM5 (0.53) | GRM5KDM4ELMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |