Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920978 | 1.00 | GRM5 (0.71) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3929713 | 0.87 | GRM5 (0.57) | GRM5KDM4EALDH1A1HTTCRHR1 | |
| SCHEMBL30795341 | 0.87 | GRM5 (0.57) | GRM5KDM4EALDH1A1HTTCRHR1 | |
| SCHEMBL14380696 | 0.85 | GRM5 (0.71) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3928571 | 0.85 | GRM5 (0.71) | GRM5 | |
| SCHEMBL5217184 | 0.85 | GRM5 (0.71) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3922587 | 0.83 | GRM5 (1.00) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3924739 | 0.82 | GRM5 (0.67) | GRM5KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL3931406 | 0.81 | GRM5 (0.51) | GRM5KDM4E | |
| SCHEMBL3928998 | 0.78 | GRM5 (0.68) | GRM5KDM4EALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |