SCHEMBL30795698

SCHEMBL30795698

NC(=O)NC12CC(F)(C1)C2

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.38
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31424982 0.78
SCHEMBL17582410 0.77 EPHX2 (0.39) EPHX2
SCHEMBL24939427 0.75 EPHX2 (0.38) EPHX2
SCHEMBL25857001 0.75 EPHX2 (0.45) EPHX2CA2
SCHEMBL30877174 0.73 EPHX2 (0.37) EPHX2
SCHEMBL22621947 0.73 KDM4E (0.33)
SCHEMBL31174775 0.73
SCHEMBL29791363 0.71 EPHX2 (0.39) EPHX2LMNA
SCHEMBL25854704 0.70 EPHX2 (0.41) EPHX2
SCHEMBL24466750 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584250-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (VG) 2025-07-16 EP disclosed
CN-118525003-A Novel heteroaryl urea compounds as KV7.2 inhibitors 伊卡根有限责任公司 2024-08-20 CN disclosed
CN-112778183-B Nitrogen-containing ring derivative regulator, preparation method and application thereof 江苏豪森药业集团有限公司 2024-05-10 CN disclosed
WO-2024054811-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed