Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30795809 | 0.85 | EPHX1 (0.38) | EPHX1SLC6A9CYP1A2CYP2D6PKM | |
| SCHEMBL30795605 | 0.81 | EPHX1 (0.40) | EPHX1SLC6A9SLC7A5CYP1A2CYP2D6 | |
| SCHEMBL30795511 | 0.75 | SLC6A2 (0.40) | EPHX1SLC6A9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7507142 | 0.75 | CYP1A2 (0.42) | EPHX1SLC6A9SLC7A5SLC6A2SLC6A4 | |
| SCHEMBL1835163 | 0.69 | ADRB1 (0.51) | — | |
| SCHEMBL3458611 | 0.69 | EPHX1 (0.43) | EPHX1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL16963125 | 0.68 | GSR (0.49) | SLC7A5SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL27835347 | 0.68 | TAAR1 (0.46) | SLC7A5SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL3662060 | 0.67 | CYP1A2 (0.55) | EPHX1SLC7A5CYP1A2PKM | |
| SCHEMBL2846532 | 0.67 | CYP1A2 (0.55) | EPHX1SLC7A5CYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |