Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323584 | 0.86 | DDB1 (0.55) | DDB1CRBNTP53KDM4EMAPT | |
| SCHEMBL27452842 | 0.86 | CRBN (0.42) | DDB1CRBNKDM4EMAPT | |
| SCHEMBL26954254 | 0.82 | CRBN (0.52) | DDB1CRBNGPR119 | |
| SCHEMBL26930906 | 0.82 | CRBN (0.52) | DDB1CRBNGPR119KDM4EMAPT | |
| SCHEMBL27453593 | 0.82 | CRBN (0.52) | DDB1CRBNGPR119KDM4EMAPT | |
| SCHEMBL26930734 | 0.82 | CRBN (0.52) | DDB1CRBNGPR119KDM4EMAPT | |
| SCHEMBL30796994 | 0.82 | CRBN (0.52) | DDB1CRBNGPR119KDM4EMAPT | |
| SCHEMBL27452912 | 0.81 | DDB1 (0.48) | DDB1CRBNTP53KDM4EMAPT | |
| SCHEMBL25169721 | 0.81 | DDB1 (0.52) | DDB1CRBNTP53GPR119KDM4E | |
| SCHEMBL25036235 | 0.81 | DDB1 (0.55) | DDB1CRBNGPR119PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |