Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844916 | 0.67 | CYP17A1 (0.44) | FLT3POLBALDH1A1HPGDMEN1 | |
| SCHEMBL3085669 | 0.67 | IDO1 (0.71) | FLT3POLBALDH1A1HPGDKDM4E | |
| SCHEMBL5412317 | 0.62 | FLT3 (0.46) | FLT3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3702960 | 0.60 | GRIA1 (0.38) | POLBALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4204691 | 0.60 | ALDH1A1 (0.44) | FLT3POLBALDH1A1HPGDMEN1 | |
| SCHEMBL14844909 | 0.59 | CYP17A1 (0.42) | FLT3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL27741873 | 0.58 | MEN1 (0.42) | FLT3POLBALDH1A1HPGDMEN1 | |
| SCHEMBL22777380 | 0.58 | ADORA2A (0.47) | MAPK14PTGS2CSNK1EADORA2ACCNT1 | |
| SCHEMBL3462133 | 0.58 | HDAC4 (0.46) | POLBALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15473570 | 0.58 | CYP17A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790741-B2 | Imidazothiazoles and imidazoxazoles | ABBOTT LABORATORIES (US) | 2010-09-07 | — | — | US | disclosed |
| US-20080161341-A1 | Novel imidazothiazoles and imidazoxazoles | ABBVIE INC. | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161341-A1 | Novel imidazothiazoles and imidazoxazoles | MAP3K1, MAP3K19, MAP3K5 | FLT3 273/4885POLB 2315/4885ALDH1A1 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.