Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570024 | 0.79 | CKS1B (0.61) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| Ammonia Solution, Strong SCHEMBL3561132 | 0.78 | CKS1B (0.60) | MAPTALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL26669459 | 0.77 | MAPT (0.47) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| SCHEMBL14686997 | 0.76 | SMPD3 (0.49) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| SCHEMBL25193207 | 0.76 | MAPT (0.52) | MAPTALDH1A1LMNACKS1BSKP1 | |
| SCHEMBL3565243 | 0.76 | GPR119 (0.51) | SMARCA2SMARCA4PBRM1CKS1BSKP1 | |
| SCHEMBL17236188 | 0.75 | MAPT (0.54) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| SCHEMBL10317314 | 0.75 | POLB (0.58) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| SCHEMBL31465821 | 0.75 | RET (0.49) | MAPTALDH1A1LMNASMARCA2SMARCA4 | |
| SCHEMBL31210727 | 0.75 | KCNH2 (0.45) | MAPTALDH1A1LMNASMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |