Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797093 | 0.85 | CRBN (0.52) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797273 | 0.83 | CRBN (0.64) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797150 | 0.82 | CRBN (0.35) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797106 | 0.82 | CRBN (0.63) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797095 | 0.82 | CRBN (0.58) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797108 | 0.82 | CRBN (0.58) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797107 | 0.82 | CRBN (0.58) | CRBNIKZF2 | |
| SCHEMBL31546779 | 0.81 | CRBN (0.48) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797297 | 0.81 | CRBN (0.62) | CRBNIKZF2 | |
| SCHEMBL30797338 | 0.81 | CRBN (0.64) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |