Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | GOT1 | P17174 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13737287 | 1.00 | MAPT (0.64) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL14685427 | 0.87 | MAPT (0.66) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL12989341 | 0.86 | LMNA (0.71) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL5759619 | 0.83 | MEN1 (0.61) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL30101230 | 0.83 | KMT2A (0.90) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL5597699 | 0.83 | KMT2A (0.90) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL3429585 | 0.82 | MAPT (0.68) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL28406980 | 0.82 | MEN1 (0.73) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL3865228 | 0.82 | KMT2A (0.59) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL136432 | 0.82 | MEN1 (0.72) | MAPTMEN1KMT2AHTTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |