Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10098903 | 1.00 | DCK (1.00) | DCK | |
| SCHEMBL10098883 | 0.92 | DCK (0.85) | DCK | |
| SCHEMBL308191 | 0.88 | DCK (1.00) | DCK | |
| SCHEMBL10098881 | 0.88 | DCK (1.00) | DCK | |
| SCHEMBL10098893 | 0.87 | DCK (0.82) | DCK | |
| SCHEMBL10098886 | 0.86 | DCK (0.75) | DCK | |
| SCHEMBL308017 | 0.84 | DCK (0.74) | DCK | |
| SCHEMBL306525 | 0.84 | DCK (0.73) | DCK | |
| SCHEMBL307463 | 0.83 | DCK (0.71) | DCK | |
| SCHEMBL10098906 | 0.83 | DCK (0.71) | DCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093245-B2 | Anticancer agents; potent Deoxycytidine kinase inhibitors; inhibit thymidine kinase; inhibit uridine kinase; N-[3-(4-amino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-cyclopentyl]-3-bromo-benzenesulfonamide | LEXICON PHARMACEUTICALS, INC. (US) | 2012-01-10 | — | — | US | disclosed |