Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20817610 | 1.00 | ICMT (0.47) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL20817527 | 0.86 | CYP3A4 (0.51) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL30797929 | 0.83 | ICMT (0.49) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL30797818 | 0.83 | ICMT (0.52) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL20817498 | 0.83 | ICMT (0.49) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL20817556 | 0.83 | ICMT (0.52) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL30797922 | 0.81 | ICMT (0.55) | ICMTCYP3A4CYP2E1CYP2A6GRM5 | |
| SCHEMBL20817522 | 0.81 | ICMT (0.55) | ICMTCYP3A4CYP2E1CYP2A6GRM5 | |
| SCHEMBL20817589 | 0.80 | ICMT (0.47) | ICMTCYP3A4CYP2E1CYP2A6F2 | |
| SCHEMBL11929770 | 0.77 | CYP3A4 (0.67) | ICMTCYP3A4CYP2E1CYP2A6F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344284-B | Compounds useful as inhibitors of isoprene cysteine carboxymethyltransferase | 新加坡科技研究局 | 2024-03-12 | — | — | CN | disclosed |