Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24718226 | 1.00 | CNR1 (0.48) | CNR1CNR2KDM4EMAPK1CLK1 | |
| SCHEMBL30804746 | 0.88 | KDM4E (0.43) | KDM4EMAPK1CLK1NPC1RAB9A | |
| SCHEMBL20812767 | 0.85 | POLB (0.50) | KDM4ECLK1NPC1RAB9AP2RX7 | |
| SCHEMBL11833701 | 0.83 | HPGD (0.55) | CNR1CNR2KDM4EMAPK1NPC1 | |
| SCHEMBL6419790 | 0.82 | CNR2 (0.51) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL6421030 | 0.81 | ACVR1B (0.50) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25213585 | 0.79 | CA1 (0.54) | KDM4EMAPK1CLK1NPC1RAB9A | |
| SCHEMBL5777771 | 0.78 | CNR1 (0.45) | CNR1CNR2KDM4ENPC1RAB9A | |
| SCHEMBL6415236 | 0.77 | POLB (0.50) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL24353844 | 0.77 | POLB (0.44) | CNR1CNR2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |