Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.46 |
| ▸ | GRAMD1A | Q96CP6 | 6/20 | 0.38 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717372 | 1.00 | CRBN (0.46) | CRBNDDB1GRAMD1ASALL4 | |
| SCHEMBL30798452 | 1.00 | CRBN (0.46) | CRBNDDB1GRAMD1ASALL4 | |
| SCHEMBL24717379 | 1.00 | CRBN (0.46) | CRBNDDB1GRAMD1ASALL4 | |
| SCHEMBL31023249 | 0.89 | CRBN (0.48) | CRBNDDB1SALL4 | |
| SCHEMBL29874167 | 0.89 | CRBN (0.48) | CRBNDDB1SALL4 | |
| SCHEMBL23250113 | 0.89 | CRBN (0.48) | CRBNDDB1SALL4 | |
| SCHEMBL23250011 | 0.89 | CRBN (0.48) | CRBNDDB1SALL4 | |
| SCHEMBL24718670 | 0.89 | IKZF2 (0.43) | CRBNDDB1 | |
| SCHEMBL24718115 | 0.89 | IKZF2 (0.49) | CRBNDDB1SALL4 | |
| SCHEMBL31023252 | 0.89 | IKZF2 (0.49) | CRBNDDB1SALL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |