Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.48 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23250011 | 1.00 | CRBN (0.48) | CRBNDDB1IKZF2MAP1LC3BSALL4 | |
| SCHEMBL23250113 | 1.00 | CRBN (0.48) | CRBNDDB1IKZF2MAP1LC3BSALL4 | |
| SCHEMBL29874167 | 1.00 | CRBN (0.48) | CRBNDDB1IKZF2MAP1LC3BSALL4 | |
| SCHEMBL20231952 | 0.91 | CRBN (0.53) | CRBNDDB1IKZF2MAP1LC3BSALL4 | |
| SCHEMBL20046321 | 0.90 | CRBN (0.58) | CRBNDDB1MAP1LC3BSALL4ALDH1A1 | |
| SCHEMBL29367285 | 0.90 | CRBN (0.58) | CRBNDDB1MAP1LC3BSALL4ALDH1A1 | |
| SCHEMBL24717372 | 0.89 | CRBN (0.46) | CRBNDDB1SALL4 | |
| SCHEMBL24717379 | 0.89 | CRBN (0.46) | CRBNDDB1SALL4 | |
| SCHEMBL30798452 | 0.89 | CRBN (0.46) | CRBNDDB1SALL4 | |
| SCHEMBL30798514 | 0.89 | CRBN (0.46) | CRBNDDB1SALL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019369-A | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115397821-B | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118388454-A | Modulators of BCL6 proteolysis and related methods of use | 阿尔维纳斯运营股份有限公司 | 2024-07-26 | — | — | CN | disclosed |