Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798822 | 0.94 | MMP12 (0.46) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL953077 | 0.81 | MMP12 (0.56) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL252110 | 0.81 | MAPT (0.50) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL30798623 | 0.78 | POLB (0.40) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL1797944 | 0.78 | MAPT (0.44) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL30798572 | 0.78 | AR (0.39) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL1162203 | 0.76 | MMP12 (0.51) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL17137439 | 0.76 | SRC (0.47) | ALDH1A1CHEK1SRC | |
| SCHEMBL31423376 | 0.75 | MAPT (0.63) | MMP12KDM4EALDH1A1MAPTAPEX1 | |
| SCHEMBL2268967 | 0.75 | MMP12 (0.50) | MMP12KDM4EALDH1A1MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |