Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687134 | 0.81 | KDM4E (0.44) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL4606421 | 0.78 | MMP12 (0.47) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL953077 | 0.77 | MMP12 (0.56) | QPCTMMP12POLBKDM4EMAPT | |
| SCHEMBL22533358 | 0.75 | QPCT (0.50) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL7020232 | 0.73 | KMT2A (0.45) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL5374095 | 0.73 | QPCT (0.48) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL5374097 | 0.73 | QPCT (0.48) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL30798676 | 0.73 | HDAC6 (0.51) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL30798669 | 0.73 | QPCT (0.48) | QPCTMMP12KMT2ANPC1RAB9A | |
| SCHEMBL1975515 | 0.72 | QPCT (0.50) | QPCTMMP12KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |