SCHEMBL30798736

SCHEMBL30798736

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.53
▸ NTSR2 O95665 4/20 0.52
▸ NTSR1 P30989 4/20 0.52
▸ SORT1 Q99523 3/20 0.48
▸ LNPEP Q9UIQ6 3/20 0.47
▸ ANPEP P15144 2/20 0.47
▸ VIPR2 P41587 2/20 0.46
▸ NPY1R P25929 1/20 0.46
▸ NPY2R P49146 1/20 0.46
▸ NPY4R P50391 1/20 0.46
▸ CASP1 P29466 1/20 0.46
▸ CASP3 P42574 1/20 0.46
▸ CASP4 P49662 1/20 0.46
▸ CASP5 P51878 1/20 0.46
▸ CASP9 P55211 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ CASP8 Q14790 1/20 0.46
▸ CASP10 Q92851 1/20 0.46
▸ VIPR1 P32241 1/20 0.45
▸ CTSD P07339 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29679828 0.93 F2 (0.52) F2NTSR2NTSR1SORT1LNPEP
SCHEMBL30092922 0.89 NPY4R (0.54) F2NTSR2NTSR1VIPR2NPY1R
SCHEMBL30063663 0.89 NTSR2 (0.54) F2NTSR2NTSR1SORT1LNPEP
SCHEMBL29462368 0.88 VIPR2 (0.50) F2NTSR2NTSR1VIPR2VIPR1
SCHEMBL30741250 0.88 VIPR2 (0.56) F2VIPR2CASP1CASP3CASP4
SCHEMBL30092917 0.88 NPY4R (0.56) F2NTSR2NTSR1NPY1RNPY2R
SCHEMBL29973963 0.87 F2 (0.52) F2NTSR2NTSR1
SCHEMBL29974829 0.87 F2 (0.52) F2NTSR2NTSR1
SCHEMBL29974534 0.86 NTSR2 (0.54) F2NTSR2NTSR1SORT1NPY1R
SCHEMBL29974987 0.86 NTSR2 (0.54) F2NTSR2NTSR1SORT1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116984-A1 MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION NATIONAL SCIENCE FOUNDATION 2024-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116984-A1 MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION PRNP, MAPT, APP F2 3097/4885NTSR2 1511/4885NTSR1 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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