SCHEMBL30741250

SCHEMBL30741250

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 7/20 0.56
▸ VIPR1 P32241 5/20 0.55
▸ F2 P00734 2/20 0.55
▸ BACE1 P56817 4/20 0.54
▸ BACE2 Q9Y5Z0 3/20 0.54
▸ GLP1R P43220 2/20 0.50
▸ CASP1 P29466 1/20 0.49
▸ CASP3 P42574 1/20 0.49
▸ CASP4 P49662 1/20 0.49
▸ CASP5 P51878 1/20 0.49
▸ CASP9 P55211 1/20 0.49
▸ CASP6 P55212 1/20 0.49
▸ CASP8 Q14790 1/20 0.49
▸ CASP10 Q92851 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362779 0.97 VIPR2 (0.53) VIPR2VIPR1F2BACE1BACE2
SCHEMBL30543189 0.97 VIPR2 (0.53) VIPR2VIPR1F2BACE1BACE2
SCHEMBL29425538 0.95 VIPR2 (0.51) VIPR2VIPR1F2BACE1BACE2
SCHEMBL29462368 0.93 VIPR2 (0.50) VIPR2VIPR1F2BACE1BACE2
SCHEMBL29466598 0.90 VIPR2 (0.54) VIPR2VIPR1F2BACE1BACE2
SCHEMBL29520980 0.89 VIPR2 (0.54) VIPR2VIPR1F2BACE1BACE2
SCHEMBL29778027 0.89 VIPR2 (0.54) VIPR2VIPR1F2BACE1BACE2
SCHEMBL30622615 0.89 BACE1 (0.58) F2BACE1BACE2CASP1CASP3
SCHEMBL30798736 0.88 F2 (0.53) VIPR2VIPR1F2CASP1CASP3
SCHEMBL30168728 0.87 TFPI (0.58) VIPR2VIPR1F2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024504-A1 SITE-SELECTIVE LYSINE ACETYLATION OF HUMAN IMMUNOGLOBULIN G AND IgG-RELATED PRODUCTS FOR IMMUNOTHERAPY THE CHINESE UNIVERSITY OF HONG KONG (CN) 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024504-A1 SITE-SELECTIVE LYSINE ACETYLATION OF HUMAN IMMUNOGLOBULIN G AND IgG-RELATED PRODUCTS FOR IMMUNOTHERAPY FCGR3B, FCGR2A, FCGR1A VIPR2 3552/4885VIPR1 3426/4885F2 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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