Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CCNH | P51946 | 1/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476588 | 0.84 | AR (0.52) | ARPARP1CHEK2FGFR1PRKCI | |
| Hydrochloric Acid SCHEMBL4541624 | 0.83 | AR (0.51) | ARPARP1CHEK2FGFR1PKN2 | |
| SCHEMBL29172042 | 0.82 | ERN1 (0.50) | ERN1FYNCDK1CDK2NEK2 | |
| SCHEMBL30848121 | 0.81 | AR (0.57) | ARPARP1ERN1FYNCHEK2 | |
| SCHEMBL29172008 | 0.81 | AR (0.57) | ARPARP1ERN1FYNCHEK2 | |
| SCHEMBL30848223 | 0.80 | AR (0.53) | ARPARP1CHEK2KDM4EALDH1A1 | |
| SCHEMBL29171940 | 0.80 | AR (0.53) | ARPARP1CHEK2KDM4EALDH1A1 | |
| SCHEMBL2208560 | 0.79 | CHEK2 (0.53) | CHEK2PKN2 | |
| SCHEMBL6008269 | 0.79 | MAPT (0.50) | PRKCIKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL31143361 | 0.79 | MAPT (0.50) | PRKCIKDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051354-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州沪云新药研发股份有限公司 | 2024-03-14 | — | — | WO | disclosed |