Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 6/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.49 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474515 | 0.92 | QPCT (0.60) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL2457365 | 0.90 | QPCT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL13373351 | 0.88 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL13373486 | 0.88 | PARP1 (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL28178019 | 0.88 | PSMD11 (0.49) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL7021134 | 0.88 | QPCT (0.49) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL28178021 | 0.88 | PARP1 (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL25912038 | 0.88 | PARP1 (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL23123086 | 0.87 | QPCT (0.51) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL22418755 | 0.87 | QPCT (0.47) | MAPTKDM4EALDH1A1APEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177141-B | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | claimed |
| EP-2575968-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | Summit Corporation Plc (GB) | 2013-04-10 | — | — | EP | claimed |
| WO-2011151621-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | SUMMIT CORPORATION PLC (GB) | 2011-12-08 | — | — | WO | claimed |
| EP-4277604-A1 | SOLID TABLET DOSAGE FORM OF RIDINILAZOLE | Summit (Oxford) Limited (GB) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022153246-A1 | SOLID TABLET DOSAGE FORM OF RIDINILAZOLE | SUMMIT (OXFORD) LTD. (GB) | 2022-07-21 | — | — | WO | disclosed |
| CN-112274481-A | Pantoprazole sodium composition for injection and preparation method thereof | 海南卫康制药(潜山)有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-108623806-B | Polybenzimidazole with side ammonium groups, anion exchange membrane thereof and preparation method thereof | 大连理工大学 | 2020-08-25 | — | — | CN | disclosed |
| EP-3011960-B1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASE | SUMMIT THERAPEUTICS PLC (GB) | 2020-04-15 | — | — | EP | disclosed |
| EP-2459545-B1 | EPOXIDATION PROCESS | SOUTH BANK UNIV ENTERPRISES LIMITED (GB) | 2019-03-27 | — | — | EP | disclosed |
| CN-108026670-A | Phosphorylated PBI fibers | PBI性能产品公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-105377950-B | Process for preparing polybenzimidazole | PBI性能产品公司 | 2017-12-29 | — | — | CN | disclosed |
| EP-2481119-A1 | PROTON EXCHANGE MEMBRANE COMPRISING POLYMER BLENDS FOR USE IN HIGH TEMPERATURE PROTON EXCHANGE MEMBRANE FUEL CELLS | EWE-Forschungszentrum Für Energietechnologie E.V. (DE) | 2012-08-01 | — | — | EP | disclosed |
| EP-2459545-A2 | PROCESS | South Bank University Enterprises Limited (GB) | 2012-06-06 | — | — | EP | disclosed |
| US-20120136165-A1 | PROCESS | SOUTH BANK UNIVERSITY ENTERPRISES LTD. (GB) | 2012-05-31 | — | — | US | disclosed |
| WO-2011151618-A2 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASE | SUMMIT CORPORATION PLC (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011012869-A2 | PROCESS | SOUTH BANK UNIVERSITY ENTERPRISES LTD (GB) | 2011-02-03 | — | — | WO | disclosed |
| EP-1719200-A2 | HIGH-PERFORMANCE MEMBRANE ELECTRODE UNIT AND THE USE THEREOF IN FUEL CELLS | Pemeas GmbH (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005081351-A2 | HIGH-PERFORMANCE MEMBRANE ELECTRODE UNIT AND THE USE THEREOF IN FUEL CELLS | PEMEAS GMBH (DE) | 2005-09-01 | — | — | WO | disclosed |
| EP-0511187-B1 | Process for the preparation of 1H-benzimidazoles | UCB SA (BE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0511187-A1 | Process for the preparation of 1H-benzimidazoles | U C B, S.A. (BE) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136165-A1 | PROCESS | AOX1, NOX4, SMOX | MAPT 3597/4885KDM4E 551/4885ALDH1A1 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.