Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 10/20 | 0.90 |
| ▸ | ATIC | P31939 | 2/20 | 0.72 |
| ▸ | TYMS | P04818 | 2/20 | 0.72 |
| ▸ | GART | P22102 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dideazafolate SCHEMBL10036542 | 1.00 | DHFR (0.90) | DHFRATICTYMSGART | |
| SCHEMBL29692260 | 0.95 | DHFR (1.00) | DHFRATICTYMSGART | |
| SCHEMBL6449047 | 0.92 | DHFR (0.77) | DHFRATICTYMSGART | |
| SCHEMBL24413576 | 0.91 | DHFR (0.76) | DHFRATICTYMSGART | |
| SCHEMBL24413587 | 0.91 | DHFR (0.76) | DHFRATICTYMSGART | |
| SCHEMBL410474 | 0.91 | DHFR (0.76) | DHFRATICTYMSGART | |
| SCHEMBL15507841 | 0.91 | DHFR (0.75) | DHFRATICTYMSGART | |
| SCHEMBL29617327 | 0.90 | DHFR (0.74) | DHFRATICTYMSGART | |
| SCHEMBL408871 | 0.89 | DHFR (0.72) | DHFRATICTYMSGART | |
| Dideazafolate SCHEMBL13125706 | 0.88 | DHFR (0.70) | DHFRATICTYMSGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989138-B | Humanized anti-Prostate Specific Membrane Antigen (PSMA) antibody drug conjugates | AMBRX公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117440833-A | anti-HER 2 antibody-drug conjugates and uses thereof | AMBRX公司 | 2024-01-23 | — | — | CN | disclosed |