Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264385 | 0.86 | BRD4 (0.48) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL7986840 | 0.86 | BRD4 (0.48) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL21542270 | 0.85 | KDM1A (0.44) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL20182780 | 0.85 | KDM1A (0.44) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL21542203 | 0.85 | KDM1A (0.44) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL20165949 | 0.85 | KDM1A (0.44) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL21542268 | 0.85 | KDM1A (0.44) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL21284828 | 0.84 | GAA (0.45) | GAAEPHX2KDM1AMAOBKMT2A | |
| SCHEMBL6899464 | 0.84 | EPHX2 (0.43) | GAAEPHX2KDM1AMAOBSSTR4 | |
| SCHEMBL21178544 | 0.83 | GAA (0.44) | GAAEPHX2KDM1AMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038282-A1 | 2-AZA- AND 2-OXABICYCLO[2.1.1]HEXANE DERIVATIVES AS FACTOR XIIA ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |