SCHEMBL30799385

SCHEMBL30799385

Cc1cc(CC(N)C(=O)N2CCN(C3CCN(C)CC3)CC2)cc2cn[nH]c12

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.58
CALCRL Q16602 1/20 0.58
CALCA P06881 19/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748868 1.00 CYP3A4 (0.58) CYP3A4CALCRLCALCA
SCHEMBL5660417 1.00 CYP3A4 (0.58) CYP3A4CALCRLCALCA
SCHEMBL5658602 0.96 CALCA (0.56) CYP3A4CALCRLCALCA
SCHEMBL5661665 0.96 CALCRL (0.56) CYP3A4CALCRLCALCA
Trifluoroacetic Acid SCHEMBL31430917 0.94 CYP3A4 (0.53) CYP3A4CALCRLCALCA
Trifluoroacetic Acid SCHEMBL31180093 0.94 CYP3A4 (0.53) CYP3A4CALCRLCALCA
SCHEMBL5658251 0.93 CALCA (0.56) CYP3A4CALCRLCALCA
SCHEMBL3605516 0.92 CALCRL (0.57) CALCRLCALCA
SCHEMBL5660491 0.91 CALCA (0.53) CALCRLCALCA
SCHEMBL4862077 0.90 CYP3A4 (0.48) CYP3A4CALCRLCALCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551081-A New preparation method of migraine therapeutic drug 北京康立生医药技术开发有限公司 2024-02-13 CN claimed
CN-117551081-A New preparation method of migraine therapeutic drug 北京康立生医药技术开发有限公司 2024-02-13 CN disclosed