Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.59 |
| ▸ | MMP8 | P22894 | 3/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30830320 | 0.94 | ERAP2 (0.58) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL30788012 | 0.93 | ERAP2 (0.64) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL29630749 | 0.93 | ERAP2 (0.61) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL30051359 | 0.91 | ACE (0.64) | MMP9MMP8ACEOPRM1OPRD1 | |
| SCHEMBL29828471 | 0.90 | KDM4E (0.59) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL30050850 | 0.90 | ECE1 (0.65) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL29749345 | 0.90 | ACE (0.63) | MMP9MMP8ACEERAP2ECE1 | |
| SCHEMBL30788020 | 0.89 | ECE1 (0.61) | MMP9MMP8MMP2MMP1ACE | |
| SCHEMBL10753338 | 0.89 | ACE (0.62) | MMP9MMP8ACEOPRM1OPRD1 | |
| SCHEMBL31720493 | 0.88 | ERAP2 (0.67) | MMP9MMP8MMP2MMP1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | MMP9 244/4885MMP8 446/4885MMP2 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.