Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748989 | 0.95 | TDP1 (0.57) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4454446 | 0.91 | TDP1 (0.58) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL1527196 | 0.91 | TDP1 (0.58) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL4740139 | 0.89 | TDP1 (0.60) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL30845900 | 0.89 | TDP1 (0.49) | HLCSTDP1MEN1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL30315673 | 0.88 | HLCS (0.69) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL900650 | 0.85 | TDP1 (0.57) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL22793211 | 0.85 | HLCS (0.73) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL18007530 | 0.83 | TDP1 (0.50) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL12990072 | 0.83 | HLCS (0.72) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |