Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL4678985 | 1.00 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL13583770 | 0.98 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL585499 | 0.98 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL9192760 | 0.94 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL3860952 | 0.94 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL6287569 | 0.92 | FFAR3 (0.52) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL27302377 | 0.92 | FFAR3 (0.52) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL9784657 | 0.90 | FFAR3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Toluene SCHEMBL11115673 | 0.90 | FFAR3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| P-Xylene SCHEMBL28135735 | 0.89 | FFAR3 (0.65) | HDAC3HDAC1HDAC2HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954671-B1 | POLYNUCLEOTIDE LABELLING REAGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-7795423-B2 | Polynucleotide labeling reagent | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090012279-A1 | POLYNUCLEOTIDE LABELING REAGENT | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-01-08 | — | — | US | disclosed |
| WO-2002079180-A1 | A METHOD FOR CONVERTING DIHYDROTAGETONE, A BIFUNCTIONAL ACYCLIC MONOTERPENE KETONE INTO 5-ISOBUTYL-3-METHYL-4,5-DIHYDRO-2(3H)-FURANONE AS A ANALOGUE OF NATURAL WHISKY LACTONE AND COCONUT ALDEHYDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-10-10 | — | — | WO | disclosed |
| US-5332811-A | Antitumor intermediates | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012279-A1 | POLYNUCLEOTIDE LABELING REAGENT | POLM, POLN, POLRMT | HDAC3 3767/4885HDAC1 4438/4885HDAC2 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.