Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348172 | 0.85 | HTR2A (0.56) | HTR2CMEN1KMT2A | |
| SCHEMBL26472925 | 0.85 | HTR2A (0.56) | HTR2CMEN1KMT2A | |
| SCHEMBL25722433 | 0.85 | HTR2A (0.56) | HTR2CMEN1KMT2A | |
| SCHEMBL23348066 | 0.85 | HTR2A (0.56) | HTR2CMEN1KMT2A | |
| SCHEMBL25722435 | 0.85 | HTR2A (0.56) | HTR2CMEN1KMT2A | |
| SCHEMBL24367125 | 0.84 | HTR2C (0.49) | HTR2CTACR1DRD2MEN1KMT2A | |
| SCHEMBL1515163 | 0.80 | HTR2C (0.75) | HTR2CDRD2MEN1KMT2AADRA1D | |
| SCHEMBL5017875 | 0.79 | CHRNB2 (0.47) | HTR2C | |
| SCHEMBL21912179 | 0.79 | CHRNB2 (0.47) | HTR2C | |
| SCHEMBL23323077 | 0.77 | MEN1 (0.65) | HTR2CTACR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761083-B | 5-HT for treating depression 2A Agonists | 罗福拉公司 | 2024-02-13 | — | — | CN | disclosed |