Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 7/20 | 0.35 |
| ▸ | ATR | Q13535 | 4/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801291 | 0.75 | MAPK14 (0.36) | SPR | |
| Hydrochloric Acid SCHEMBL30801274 | 0.74 | PTK6 (0.34) | — | |
| SCHEMBL24671255 | 0.72 | ITK (0.47) | ATRHRH4PARP1 | |
| SCHEMBL30066292 | 0.72 | ITK (0.47) | ATRHRH4PARP1 | |
| SCHEMBL30066339 | 0.71 | KDM4E (0.39) | HRH4 | |
| SCHEMBL31055473 | 0.62 | ITK (0.42) | ATRPARP1 | |
| SCHEMBL24671305 | 0.62 | ITK (0.42) | ATRPARP1 | |
| SCHEMBL24671303 | 0.62 | ITK (0.42) | ATRPARP1 | |
| SCHEMBL31220894 | 0.59 | PARP1 (0.63) | HRH4PARP1 | |
| SCHEMBL3087941 | 0.59 | PARP1 (0.63) | HRH4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |