Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31134484 | 0.90 | CRBN (0.55) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL27039409 | 0.89 | CRBN (0.54) | CRBNDDB1 | |
| SCHEMBL24670182 | 0.87 | CRBN (0.44) | CRBNDDB1ALDH1A1 | |
| SCHEMBL30066195 | 0.87 | CRBN (0.44) | CRBNDDB1ALDH1A1 | |
| SCHEMBL31722466 | 0.86 | CRBN (0.43) | CRBNDDB1ALDH1A1 | |
| SCHEMBL24670181 | 0.86 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL30066248 | 0.86 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL27039720 | 0.82 | DDB1 (0.58) | CRBNDDB1ALDH1A1LMNA | |
| SCHEMBL25955979 | 0.77 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL31112020 | 0.76 | CRBN (0.59) | CRBNDDB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |