SCHEMBL30801366

SCHEMBL30801366

COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cc3ccccn3)c3c(c12)OCC3

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 20/20 0.67
KAT7 O95251 19/20 0.67
KAT6B Q8WYB5 10/20 0.67
KAT5 Q92993 6/20 0.49
KAT8 Q9H7Z6 6/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25044666 1.00 KAT6A (0.67) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25562563 0.95 KAT6A (0.65) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25926522 0.87 KAT6A (0.52) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25561774 0.84 KAT6A (0.55) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30360835 0.84 KAT6A (0.55) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30184731 0.82 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25439714 0.82 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25562565 0.81 KAT6A (0.51) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25926263 0.81 KAT6A (0.52) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25046077 0.81 KAT6A (0.52) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117597341-A Sulfonamide derivative, preparation method and application thereof in medicine 江苏恒瑞医药股份有限公司 2024-02-23 CN disclosed