SCHEMBL30801445

SCHEMBL30801445

COc1cc(O)c2c(c1)C[C@@H](c1ccc(O)cc1)OC2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.66
TDP1 Q9NUW8 2/20 0.66
ALDH1A1 P00352 1/20 0.66
ADORA3 P0DMS8 1/20 0.66
MAPT P10636 1/20 0.66
ATM Q13315 1/20 0.66
TAS2R31 P59538 1/20 0.66
ABCG2 Q9UNQ0 1/20 0.58
CYP1A1 P04798 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP1B1 Q16678 2/20 0.55
KDM4E B2RXH2 1/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
CYP3A4 P08684 2/20 0.49
MEN1 O00255 1/20 0.49
ALOX12 P18054 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thunberginol C SCHEMBL23067798 0.85 CYP19A1 (0.62) CYP19A1TDP1ALDH1A1ADORA3MAPT
SCHEMBL31028346 0.81 MAOB (0.56) CYP19A1TDP1ALDH1A1ADORA3MAPT
SCHEMBL2314134 0.80 OPRD1 (0.62) MAPTKDM4EGAASMN1; SMN2OPRD1
SCHEMBL3366271 0.80 OPRD1 (0.62) MAPTKDM4EGAASMN1; SMN2OPRD1
Sakuranetin SCHEMBL555541 0.80 CYP19A1 (1.00) CYP19A1TDP1ALDH1A1ADORA3MAPT
Sakuranetin SCHEMBL29928748 0.80 CYP19A1 (1.00) CYP19A1TDP1ALDH1A1ADORA3MAPT
Sakuranetin SCHEMBL555542 0.80 CYP19A1 (1.00) CYP19A1TDP1ALDH1A1ADORA3MAPT
Sakuranetin SCHEMBL14410473 0.80 CYP19A1 (1.00) CYP19A1TDP1ALDH1A1ADORA3MAPT
Thunberginol E SCHEMBL23699014 0.79 CYP19A1 (0.68) CYP19A1ALDH1A1MAPTATMTAS2R31
Thunberginol E SCHEMBL29366907 0.79 CYP19A1 (0.68) CYP19A1ALDH1A1MAPTATMTAS2R31

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551167-B Oyster DPP-IV inhibitory peptide rich in branched chain amino acid, and preparation method and application thereof 广东海洋大学 2024-05-07 CN disclosed
CN-117551167-A Oyster DPP-IV inhibitory peptide rich in branched chain amino acid, and preparation method and application thereof 广东海洋大学 2024-02-13 CN disclosed