Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306445 | 1.00 | BRD4 (0.51) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL8842075 | 0.89 | BRD4 (0.46) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL4835670 | 0.86 | OPRM1 (0.50) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL18664545 | 0.84 | OPRM1 (0.42) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL3501478 | 0.84 | BRD4 (0.41) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL3308150 | 0.83 | KDM4E (0.40) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL13328493 | 0.82 | BRD4 (0.40) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL3304544 | 0.82 | BRD4 (0.40) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL7301462 | 0.82 | BRD4 (0.54) | BRD4SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL3305558 | 0.82 | OPRM1 (0.44) | OPRM1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551037-A | Compounds as succinate dehydrogenase inhibitors and uses thereof | 华东理工大学 | 2024-02-13 | — | — | CN | disclosed |