Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31610 | 0.90 | TDP1 (0.47) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Ammonia Solution, Strong SCHEMBL15710720 | 0.88 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27321299 | 0.88 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Hydrochloric Acid SCHEMBL27504364 | 0.88 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL1292730 | 0.86 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27411448 | 0.86 | HDAC1 (0.48) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27324536 | 0.86 | TDP1 (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28168084 | 0.86 | CHRM1 (0.48) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11254664 | 0.85 | ACE (0.40) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28259406 | 0.85 | GPR84 (0.50) | TDP1MEN1KMT2AGRIK1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112903832-B | Method for detecting dipropylmalonic acid related impurities | 四川科瑞德制药股份有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-112903832-A | Method for detecting dipropylmalonic acid related impurities | 四川科瑞德制药股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-105712901-A | Method for synthesizing optically active intermediate N-tert-butoxycarbonyl-2-amino-8-nonenoic dicyclohexylamine salt | 成都柏睿泰生物科技有限公司 | 2016-06-29 | — | — | CN | claimed |
| CN-118184508-A | Method for preparing valproic acid by diethyl malonate method | 湖南省湘中制药有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117430509-A | Preparation and hydrolysis method of 2-alkyl-2-propyl malonic acid diester | 湖南省湘中制药有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-114832013-B | Antibacterial substance and antibacterial gel for nourishing and repairing genital tract | 朵博士健康科技(杭州)有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-112903832-B | Method for detecting dipropylmalonic acid related impurities | 四川科瑞德制药股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114832013-A | Antibacterial substance and antibacterial gel for nourishing and repairing reproductive tract | 朵博士健康科技(杭州)有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-112903832-A | Method for detecting dipropylmalonic acid related impurities | 四川科瑞德制药股份有限公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2841418-B1 | (3,4-DICHLORO-PHENYL)-((S)-3-PROPYL-PYRROLIDIN-3-YL)-METHANONE HYDROCHLORIDE AND MANUFACTURING PROCESSES | HOFFMANN LA ROCHE (CH) | 2017-03-08 | — | — | EP | disclosed |
| CN-1173170-A | Matrix metalloprotease inhibitors | SYNTEX INC (US) | 1998-02-11 | — | — | CN | disclosed |
| EP-0726903-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-07-16 | — | — | EP | disclosed |
| CN-1134153-A | Matrix metalloprotease inhibitors | SYNTEX INC (US) | 1996-10-23 | — | — | CN | disclosed |
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| CN-1017426-B | Process for preparing alkyl melatonin | LILLY CO ELI (US) | 1992-07-15 | — | — | CN | disclosed |
| CN-88100478-A | alkyl melatonin | — | 1988-08-17 | — | — | CN | disclosed |
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| US-3997682-A | Oleaginous food flavored with certain alpha carboxy acids and/or esters thereof | ANDERSON, CLAYTON & CO. (US) | 1976-12-14 | — | — | US | disclosed |