SCHEMBL30801584

SCHEMBL30801584

Cn1cc(-c2ccc3c(c2)CN([C@@H]2CCC(=O)NC2=O)C3=O)nc1C1[C@H]2COC[C@@H]12

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 8/20 0.53
▸ IKZF2 Q9UKS7 10/20 0.47
▸ IKZF1 Q13422 2/20 0.47
▸ CSNK1A1 P48729 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27217248 1.00 CRBN (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217257 1.00 CRBN (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27328800 0.88 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217043 0.87 IKZF2 (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217171 0.85 IKZF2 (0.54) CRBNIKZF2IKZF1
SCHEMBL27217079 0.85 CRBN (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217075 0.85 CRBN (0.53) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217185 0.85 CRBN (0.51) CRBNIKZF2IKZF1
SCHEMBL27217003 0.84 CRBN (0.52) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27217052 0.84 CRBN (0.52) CRBNIKZF2IKZF1CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 — — EP disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 — — WO disclosed
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