SCHEMBL30801630

SCHEMBL30801630

O=C1CCC(N2Cc3cc(-c4cscc4-c4ccccc4)ccc3C2=O)C(=O)N1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 10/20 0.63
IKZF1 Q13422 3/20 0.59
CSNK1A1 P48729 2/20 0.58
IKZF2 Q9UKS7 6/20 0.52
MAP1LC3B Q9GZQ8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27216891 1.00 CRBN (0.63) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL25123250 0.89 CRBN (0.71) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL27315012 0.83 CRBN (0.63) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL27217269 0.83 CRBN (0.57) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL30801638 0.83 CRBN (0.57) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL30801597 0.83 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL27217203 0.83 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL27310700 0.83 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL23860806 0.82 CRBN (0.58) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL30133306 0.82 CRBN (0.58) CRBNIKZF1CSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed