Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801690 | 0.88 | USP30 (0.41) | USP30MEN1KMT2AMAPTBACE1 | |
| SCHEMBL30801696 | 0.83 | USP30 (0.41) | USP30MEN1KMT2AMAPTSTS | |
| SCHEMBL17712395 | 0.83 | GRIN2B (0.51) | PPARA | |
| SCHEMBL17712398 | 0.83 | GRIN2B (0.51) | PPARA | |
| SCHEMBL19839313 | 0.82 | SLC1A1 (0.38) | TACR1 | |
| SCHEMBL23342654 | 0.81 | USP30 (0.47) | USP30MEN1KMT2AMAPTBACE1 | |
| SCHEMBL23342651 | 0.81 | USP30 (0.47) | USP30MEN1KMT2AMAPTBACE1 | |
| SCHEMBL28838755 | 0.81 | USP30 (0.47) | USP30MEN1KMT2AMAPTBACE1 | |
| SCHEMBL29053811 | 0.81 | USP30 (0.47) | USP30MEN1KMT2AMAPTBACE1 | |
| SCHEMBL23342653 | 0.81 | USP30 (0.47) | USP30MEN1KMT2AMAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |