Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801856 | 1.00 | USP30 (0.42) | USP30CHEK1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL30801881 | 0.88 | USP30 (0.45) | USP30CHEK1ALDH1A1HPGD | |
| SCHEMBL30801791 | 0.88 | USP30 (0.45) | USP30CHEK1ALDH1A1HPGD | |
| SCHEMBL30801827 | 0.87 | USP30 (0.37) | USP30CHEK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30801787 | 0.87 | USP30 (0.37) | USP30CHEK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23113636 | 0.85 | USP30 (0.51) | USP30 | |
| SCHEMBL23113601 | 0.85 | USP30 (0.51) | USP30 | |
| SCHEMBL30801892 | 0.85 | USP30 (0.51) | USP30 | |
| SCHEMBL23573945 | 0.85 | USP30 (0.51) | USP30 | |
| SCHEMBL30801929 | 0.85 | USP30 (0.51) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |