Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801827 | 1.00 | USP30 (0.37) | USP30CHEK1HTR1AHTR2AHTR2C | |
| SCHEMBL30801791 | 0.90 | USP30 (0.45) | USP30CHEK1ALDH1A1MEN1LMNA | |
| SCHEMBL30801881 | 0.90 | USP30 (0.45) | USP30CHEK1ALDH1A1MEN1LMNA | |
| SCHEMBL30801856 | 0.87 | USP30 (0.42) | USP30CHEK1DRD2ALDH1A1HPGD | |
| SCHEMBL30801732 | 0.87 | USP30 (0.42) | USP30CHEK1DRD2ALDH1A1HPGD | |
| SCHEMBL30801894 | 0.85 | HDAC3 (0.36) | USP30CHEK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30801821 | 0.83 | KDR (0.38) | USP30 | |
| SCHEMBL30801831 | 0.83 | KDR (0.38) | USP30 | |
| SCHEMBL30801777 | 0.82 | HTR2C (0.38) | HTR1AHTR2AHTR2CHTR7HTR2B | |
| SCHEMBL30801874 | 0.82 | HTR2C (0.38) | HTR1AHTR2AHTR2CHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |