Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801756 | 0.86 | SLC6A2 (0.34) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL23573959 | 0.82 | F10 (0.34) | F10ADRA1DADRA1AADRA1BPDE5A | |
| SCHEMBL30801912 | 0.82 | F10 (0.34) | F10ADRA1DADRA1AADRA1BPDE5A | |
| SCHEMBL23573957 | 0.82 | F10 (0.34) | F10ADRA1DADRA1AADRA1BPDE5A | |
| SCHEMBL30801768 | 0.72 | HTR2C (0.35) | HTR2AHTR2CHTR2BALOX5APFEN1 | |
| SCHEMBL30801808 | 0.72 | HTR2C (0.35) | HTR2AHTR2CHTR2BALOX5APFEN1 | |
| SCHEMBL30801784 | 0.70 | — | — | |
| SCHEMBL23574033 | 0.69 | USP30 (0.41) | — | |
| SCHEMBL23574034 | 0.69 | USP30 (0.41) | — | |
| SCHEMBL30801791 | 0.68 | USP30 (0.45) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |