⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801749 | 0.86 | MAP4K3 (0.34) | — | |
| SCHEMBL23573927 | 0.79 | UCHL1 (0.30) | — | |
| SCHEMBL23573925 | 0.79 | UCHL1 (0.30) | — | |
| SCHEMBL30801706 | 0.78 | — | — | |
| SCHEMBL30801841 | 0.78 | — | — | |
| SCHEMBL30801869 | 0.70 | HTR2A (0.41) | — | |
| SCHEMBL23113756 | 0.69 | CHRNA7 (0.34) | — | |
| SCHEMBL30801825 | 0.69 | CHRNA7 (0.34) | — | |
| SCHEMBL30801800 | 0.69 | CHRNA7 (0.34) | — | |
| SCHEMBL30801857 | 0.68 | CHRNA7 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |