Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494202 | 0.86 | CYP2C9 (0.50) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL16975844 | 0.81 | CYP2C9 (0.50) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL5136165 | 0.77 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL3013602 | 0.77 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL4941214 | 0.77 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL23703198 | 0.77 | CYP2C9 (0.44) | CYP2C9CYP2C19CYP3A4DYRK1AMEN1 | |
| SCHEMBL11200165 | 0.65 | CYP3A4 (0.74) | CYP2C9CYP2C19CYP3A4MEN1KMT2A | |
| SCHEMBL16200176 | 0.64 | NAAA (0.41) | CYP2C9CYP2C19CYP3A4KMT2APROKR1 | |
| SCHEMBL9126671 | 0.62 | — | — | |
| SCHEMBL14218910 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105603-B | Sulfonyl diazoles and N- (fluorosulfonyl) oxazoles and methods of making the same | 特里纳普克公司 | 2024-01-30 | — | — | CN | disclosed |