Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650625 | 0.86 | SYK (0.49) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL15650624 | 0.86 | SYK (0.49) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL31390167 | 0.86 | SYK (0.47) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL22678934 | 0.84 | SYK (0.55) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL17571456 | 0.84 | SYK (0.55) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL21542158 | 0.81 | MEN1 (0.41) | CA12MEN1KMT2A | |
| SCHEMBL17571450 | 0.80 | SYK (0.56) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL19477527 | 0.80 | SYK (0.53) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL19487108 | 0.80 | SYK (0.53) | SYKAKT1CTSSCTSLCTSB | |
| SCHEMBL22678944 | 0.80 | SYK (0.56) | SYKAKT1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565815-B1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | FOCHON PHARMACEUTICALS LTD (CN) | 2024-03-13 | — | — | EP | disclosed |