Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22411271 | 0.83 | GRIN2B (0.53) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL1239998 | 0.80 | BCHE (0.61) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL20795301 | 0.80 | ALDH1A1 (0.46) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL2645047 | 0.77 | HRH3 (0.69) | BCHEACHEBACE1ALDH1A1NPSR1 | |
| SCHEMBL5460896 | 0.77 | HRH3 (0.63) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL1042778 | 0.76 | HRH3 (0.72) | BCHEACHEBACE1ALDH1A1HRH3 | |
| SCHEMBL24619072 | 0.73 | BCHE (0.54) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL5358070 | 0.73 | GRIN2B (0.58) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL17605614 | 0.73 | BCHE (0.54) | BCHEACHEBACE1KDM1AMAOA | |
| SCHEMBL3355681 | 0.73 | BCHE (0.54) | BCHEACHEBACE1KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561244-A | Isoindolinone compounds and uses thereof | 杭州格博生物医药有限公司 | 2024-02-13 | — | — | CN | disclosed |