Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 5/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200325 | 1.00 | PARP1 (0.64) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL29200323 | 0.92 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL30802646 | 0.92 | PARP1 (0.75) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL29200355 | 0.88 | PARP1 (0.64) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL29200336 | 0.86 | PARP1 (0.85) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL29200353 | 0.86 | MEN1 (0.73) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL29200373 | 0.86 | PARP1 (0.64) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL30802641 | 0.86 | PARP1 (0.64) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL30802619 | 0.86 | MEN1 (0.66) | PARP1AURKARPS6KB1AURKBMEN1 | |
| SCHEMBL30802620 | 0.86 | PARP1 (0.85) | PARP1AURKARPS6KB1AURKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |