Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.61 |
| ▸ | AURKA | O14965 | 2/20 | 0.61 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802652 | 0.88 | PARP1 (0.82) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL29200364 | 0.88 | PARP1 (0.82) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL30802612 | 0.88 | MEN1 (0.73) | PARP1AURKARPS6KB1MEN1KMT2A | |
| SCHEMBL30802622 | 0.88 | PARP1 (0.64) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL30802641 | 0.88 | PARP1 (0.64) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL29200336 | 0.88 | PARP1 (0.85) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL30802620 | 0.88 | PARP1 (0.85) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL29200373 | 0.88 | PARP1 (0.64) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL29200325 | 0.88 | PARP1 (0.64) | PARP1HIF1AAURKARPS6KB1SIRT2 | |
| SCHEMBL30311518 | 0.85 | HSD17B10 (0.63) | PARP1AURKARPS6KB1SIRT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |