⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28027848 | 0.98 | ALDH1A1 (0.50) | — | |
| SCHEMBL4915942 | 0.78 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL21803067 | 0.77 | — | — | |
| SCHEMBL8931532 | 0.77 | — | — | |
| SCHEMBL2513813 | 0.77 | SMN1; SMN2 (0.61) | — | |
| SCHEMBL24345944 | 0.77 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL25108957 | 0.76 | — | — | |
| SCHEMBL14869788 | 0.76 | — | — | |
| SCHEMBL23723791 | 0.76 | — | — | |
| SCHEMBL29772829 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777096-B | Preparation method of ze Bei Nuosi his | 江西师范大学 | 2026-05-19 | — | — | CN | claimed |
| CN-117777096-A | Preparation method of zee Bei Nuosi his | 江西师范大学 | 2024-03-29 | — | — | CN | claimed |
| CN-110372594-B | Synthesis method of 1, 3-dimethyl-1H-pyrazole-4-formic acid | 苏州汉德创宏生化科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-110372594-A | The synthetic method of 1,3- dimethyl -1H- pyrazoles -4- formic acid | 苏州汉德创宏生化科技有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-106243101-B | A kind of 1,3,4- thiadiazoles sulfide derivative and its preparation method and application | 浙江工业大学 | 2019-05-24 | — | — | CN | claimed |
| JP-1168673-A | — | — | None | — | — | JP | disclosed |
| CN-117777096-B | Preparation method of ze Bei Nuosi his | 江西师范大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-117777096-B | Preparation method of ze Bei Nuosi his | 江西师范大学 | 2026-05-19 | — | — | CN | disclosed |
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-12624027-B2 | Salts and polymorphic forms of 6-chloro-7-(4-(4-chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine | ELLIPSES PHARMA LTD (GB) | 2026-05-12 | — | — | US | disclosed |
| EP-4727934-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| US-20260069602-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ACONCAGUA BIO INC (US) | 2026-03-12 | — | — | US | disclosed |
| EP-0752992-B1 | IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AVENTIS PHARMA SA (FR) | 2001-05-30 | — | — | EP | disclosed |
| EP-1020441-A1 | N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5807859-A | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1998-09-15 | — | — | US | disclosed |
| WO-1997025327-A1 | 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-4-ONE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1997-07-17 | — | — | WO | disclosed |
| EP-0752992-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026350-A1 | IMIDAZO(1,2-A)INDENO(1,2-E)PYRAZINE-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | disclosed |
| JP-H01168673-A | PRODUCTION OF 1,3-DIALKYLPYRAZOLE-4-ALDEHYDES | MITSUI TOATSU CHEM INC | 1989-07-04 | — | — | JP | disclosed |
| CN-86108691-A | Pyrazole oxime derivatives, process for their preparation and their use | NIHON NOHYAKU CO LTD (JP) | 1988-01-20 | — | — | CN | disclosed |