SCHEMBL30803061

SCHEMBL30803061

O=C(OCc1ccccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 4/20 0.57
SLC5A2 P31639 5/20 0.56
SLC5A1 P13866 3/20 0.56
HIF1A Q16665 1/20 0.51
TYR P14679 2/20 0.48
TYMP P19971 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803032 0.89 SLC28A3 (0.53) SLC28A3SLC5A2SLC5A1HIF1ATYR
SCHEMBL7184467 0.81 SLC28A3 (0.51) SLC28A3SLC5A2SLC5A1HIF1ATYR
SCHEMBL4652290 0.80 SLC28A3 (0.55) SLC28A3SLC5A2SLC5A1HIF1ATYR
SCHEMBL7193412 0.80 MAOB (0.54) SLC28A3SLC5A2SLC5A1HIF1A
SCHEMBL1075010 0.80 SLC28A3 (0.49) SLC28A3SLC5A2SLC5A1HIF1A
Salicin SCHEMBL8067421 0.79 SLC5A2 (0.61) SLC28A3SLC5A2SLC5A1HIF1ATYR
Salicin SCHEMBL16238042 0.79 SLC28A3 (0.53) SLC28A3SLC5A2SLC5A1HIF1ATYMP
SCHEMBL8657750 0.78 SLC28A3 (0.69) SLC28A3SLC5A2SLC5A1HIF1ATYR
SCHEMBL1706261 0.78 SLC28A3 (0.69) SLC28A3SLC5A2SLC5A1HIF1ATYR
SCHEMBL7181752 0.78 SLC28A3 (0.69) SLC28A3SLC5A2SLC5A1HIF1ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024033288-A1 SALICIN DERIVATIVES AS INHIBITORS OF SGLT2 Société des Produits Nestlé S.A. (CH) 2024-02-15 WO claimed
WO-2024033288-A1 SALICIN DERIVATIVES AS INHIBITORS OF SGLT2 Société des Produits Nestlé S.A. (CH) 2024-02-15 WO disclosed