SCHEMBL7184467

SCHEMBL7184467

O=C(OCOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 2/20 0.51
SLC5A1 P13866 2/20 0.47
SLC5A2 P31639 1/20 0.47
MAOB P27338 1/20 0.47
PTPN1 P18031 1/20 0.47
HIF1A Q16665 1/20 0.45
TYR P14679 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
LGALS9 O00182 1/20 0.43
LGALS1 P09382 1/20 0.43
LGALS3 P17931 1/20 0.43
LGALS7; LGALS7B P47929 1/20 0.43
APP P05067 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7193412 0.89 MAOB (0.54) SLC28A3SLC5A1SLC5A2MAOBPTPN1
SCHEMBL7193401 0.87 TDP1 (0.57) SLC28A3SLC5A1SLC5A2MAOBPTPN1
SCHEMBL940121 0.87 TDP1 (0.57) SLC28A3SLC5A1SLC5A2MAOBPTPN1
SCHEMBL4652290 0.85 SLC28A3 (0.55) SLC28A3SLC5A1SLC5A2MAOBPTPN1
SCHEMBL30803061 0.81 SLC28A3 (0.57) SLC28A3SLC5A1SLC5A2HIF1ATYR
SCHEMBL940128 0.81 TYR (0.50) SLC28A3SLC5A1SLC5A2TYR
SCHEMBL30803032 0.79 SLC28A3 (0.53) SLC28A3SLC5A1SLC5A2HIF1ATYR
SCHEMBL7193379 0.76 SLC28A3 (0.49) SLC28A3SLC5A1SLC5A2HIF1ATYR
SCHEMBL19754923 0.76 TDP1 (0.49) SLC28A3TDP1
SCHEMBL6931717 0.76 TDP1 (0.49) SLC28A3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289489-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM Ltd. (CH) 2003-03-12 EP disclosed
WO-2001091715-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM LTD. (CH) 2001-12-06 WO disclosed